{"id":5138,"date":"2021-08-24T11:20:54","date_gmt":"2021-08-24T02:20:54","guid":{"rendered":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/?p=5138"},"modified":"2021-08-24T11:20:54","modified_gmt":"2021-08-24T02:20:54","slug":"%e3%83%9f%e3%83%88%e3%82%b3%e3%83%b3%e3%83%89%e3%83%aa%e3%82%a2%e3%82%92%e7%8b%99%e3%81%84%e6%92%83%e3%81%a1%e3%81%99%e3%82%8b%e7%99%8c%e5%85%89%e6%b2%bb%e7%99%82%e6%b3%95%e3%81%ae%e9%96%8b%e7%99%ba","status":"publish","type":"post","link":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/5138.html","title":{"rendered":"\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u72d9\u3044\u6483\u3061\u3059\u308b\u764c\u5149\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u306b\u6210\u529f \uff5e\u526f\u4f5c\u7528\u306e\u5c11\u306a\u3044\u764c\u6cbb\u7642\u3092\uff0c\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306b\u85ac\u3092\u904b\u3076\u6280\u8853\u958b\u767a\u3067\uff01\uff5e"},"content":{"rendered":"<h2><span style=\"color: #000000;\"><strong>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u72d9\u3044\u6483\u3061\u3059\u308b\u764c\u5149\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u306b\u6210\u529f<br \/>\n\uff5e\u526f\u4f5c\u7528\u306e\u5c11\u306a\u3044\u764c\u6cbb\u7642\u3092\uff0c\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306b\u85ac\u3092\u904b\u3076\u6280\u8853\u958b\u767a\u3067\uff01\uff5e<br \/>\n<\/strong><\/span><\/h2>\n<p>\u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u85ac\u5b66\u7814\u7a76\u9662\u306e\u5c71\u7530\u52c7\u78e8\u51c6\u6559\u6388\uff0c\u539f\u5cf6\u79c0\u5409\u6559\u6388\u3068\u96fb\u5b50\u79d1\u5b66\u7814\u7a76\u6240\u306e\u9ad8\u91ce\u52c7\u592a\u51c6\u6559\u6388\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\uff0c\u5149\u5897\u611f\u5206\u5b50 (Photosensitizer, PS)\u3092\u642d\u8f09\u3057\u305f\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a19\u7684\u578b\u30ca\u30ce\u30ab\u30d7\u30bb\u30eb\u306e\u69cb\u7bc9\u306b\u6210\u529f\u3057\uff0c\u30d2\u30c8\u7531\u6765\u306e\u764c\u3092\u62c5\u6301\u3059\u308b\u30de\u30a6\u30b9\u3092\u7528\u3044\u305f\u691c\u8a3c\u5b9f\u9a13\u3092\u884c\u3044\uff0c\u300c\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u72d9\u3044\u6483\u3061\u3059\u308b\u764c\u5149\u6cbb\u7642\u6226\u7565\u300d\u306e\u6709\u7528\u6027\u3092\u793a\u3059\u3053\u3068\u306b\u6210\u529f\u3057\u307e\u3057\u305f\u3002<\/p>\n<h3><span style=\"color: #000000;\"><strong>\u30dd\u30a4\u30f3\u30c8<\/strong><\/span><\/h3>\n<p>\u25cf\u764c\u5149\u6cbb\u7642\u7528\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u6a19\u7684\u578b\u30ca\u30ce\u30ab\u30d7\u30bb\u30eb\u306e\u958b\u767a\u306b\u6210\u529f\u3002<br \/>\n\u25cf\u62c5\u764c\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u3092\u7528\u3044\u305f\u6cbb\u7642\u52b9\u679c\u306e\u691c\u8a3c\u5b9f\u9a13\u306b\u304a\u3044\u3066\uff0c\u5358\u56de\u6295\u4e0e\u3067\u764c\u7d30\u80de\u306e\u6210\u9577\u3092\u8457\u3057\u304f\u6291\u5236\u3002<br \/>\n\u25cf\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u72d9\u3063\u305f\u85ac\u5264\u8010\u6027\u764c\u306e\u65b0\u3057\u3044\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u306b\u671f\u5f85\u3002<\/p>\n<h3><span style=\"color: #000000;\"><strong>\u7814\u7a76\u6210\u679c\u306e<\/strong><strong>\u6982\u8981<\/strong><\/span><\/h3>\n<p>\u764c\u5149\u6cbb\u7642\u306f\uff0c\u60a3\u90e8\u5207\u9664\u3092\u884c\u308f\u305a\u306b\u9078\u629e\u90e8\u4f4d\u306e\u764c\u7d44\u7e54\u3092\u6b7b\u6ec5\u3055\u305b\u308b\u305f\u3081\uff0c\u60a3\u8005\u306e\u8eab\u4f53\u7684\u8ca0\u62c5\u304c\u5c11\u306a\u3044\u6cbb\u7642\u6cd5\u3068\u3057\u3066\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u4e00\u65b9\u3067\uff0c\u73fe\u72b6\u306e\u5149\u6cbb\u7642\u6cd5\u3067\u306f\uff0c\u6bba\u3057\u304d\u308c\u306a\u304b\u3063\u305f\u764c\u7d30\u80de\u304c\u5897\u6b96\u3059\u308b\u3053\u3068\u306b\u3088\u308b\u8010\u6027\u764c\u767a\u751f\u30ea\u30b9\u30af\u304c\u3042\u308a\uff0c\u305d\u308c\u3092\u89e3\u6c7a\u3059\u308b\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u304c\u671b\u307e\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u3053\u3067\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\uff0c\u764c\u7d30\u80de\u306e\u30a8\u30cd\u30eb\u30ae\u30fc\u5de5\u5834\u3067\u3042\u308b\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u7834\u58ca\u3059\u308b\u65b0\u305f\u306a\u764c\u5149\u6cbb\u7642\u306e\u691c\u8a3c\u3092\u8a66\u307f\u307e\u3057\u305f\u3002\u5149\u7167\u5c04\u306b\u3088\u3063\u3066\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u5185\u3067\u6d3b\u6027\u9178\u7d20\u767a\u751f\u3092\u8a98\u5c0e\u3059\u308bPS (rTPA, \u7279\u98582018-172698)\u3092\uff0c\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u578b\u30ca\u30ce\u30ab\u30d7\u30bb\u30eb (MITO-Porter, \u7279\u8a31\u7b2c5067733\u53f7)\u3092\u7528\u3044\uff0c\u30d2\u30c8\u820c\u764c\u7d30\u80de\uff08SAS cell\uff09\u306e\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3078\u9001\u9054\u3057\u307e\u3057\u305f\u3002SAS cell\u3092\u76ae\u4e0b\u79fb\u690d\u3057\u305f\u62c5\u764c\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u3092\u4f5c\u6210\u30fb\u8a55\u4fa1\u3057\u305f\u7d50\u679c\uff0cMITO-Porter (rTPA)\u6295\u4e0e\u30fb\u5149\u7167\u5c04\u7fa4\u306b\u304a\u3044\u3066\uff0c\u764c\u306e\u5897\u6b96\u3092\u8457\u3057\u304f\u6291\u5236\u3059\u308b\u6cbb\u7642\u52b9\u679c\u3092\u89b3\u5bdf\u3057\u307e\u3057\u305f\u3002<\/p>\n<p><span style=\"color: #000000;\">\u672c\u7814\u7a76\u3067\u63a1\u7528\u3059\u308b\u300c\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u72d9\u3044\u6483\u3061\u3059\u308b\u764c\u6cbb\u7642\u6226\u7565\u300d\u306f\u65e2\u5b58\u85ac\u306e\u6297\u764c\u4f5c\u7528\u6a5f\u5e8f\u3068\u7570\u306a\u308a\uff0c\u85ac\u5264\u8010\u6027\u764c\u306e\u6cbb\u7642\u306b\u3082\u6709\u7528\u3067\u3042\u308b\u3068\u671f\u5f85\u3055\u308c\u307e\u3059\u3002\u307e\u305f\uff0c\u764c\u7d30\u80de\u306b\u30d4\u30f3\u30dd\u30a4\u30f3\u30c8\u306b\u6297\u764c\u5264\u3092\u904b\u3076\u30ca\u30ce\u30ab\u30d7\u30bb\u30eb\u306f\u6b63\u5e38\u7d30\u80de\u3078\u306e\u4fb5\u8972\u6027\u3092\u6291\u3048\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u308b\u305f\u3081\uff0c\u300c\u52b9\u679c\u304c\u3067\u3066\u3044\u308b\u306e\u306b\u526f\u4f5c\u7528\u3067\u6cbb\u7642\u3092\u65ad\u5ff5\u300d\u306a\u3069\u306e\u554f\u984c\u70b9\u306e\u89e3\u6c7a\u306b\u3082\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3055\u3089\u306b\uff0c\u591a\u5f69\u306a\u6a5f\u80fd\u3092\u6709\u3059\u308b\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u6a19\u7684\u3068\u3057\u305f\u5275\u85ac\u958b\u767a\u306e\u533b\u7642\u7528\u30ca\u30ce\u30ab\u30d7\u30bb\u30eb\u306e\u57fa\u76e4\u6280\u8853\u3068\u3057\u3066\u3082\u8ca2\u732e\u3067\u304d\u308b\u3068\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/span><\/p>\n<p><span style=\"color: #000000;\">\u672c\u7814\u7a76\u6210\u679c\u306f\uff0c2021\u5e748\u670821\u65e5\uff08\u571f\uff09\u516c\u958b\u306e<a href=\"https:\/\/doi.org\/10.1039\/D1NA00427A\">Nanoscale Advances\u8a8c(https:\/\/doi.org\/10.1039\/D1NA00427A)<\/a>\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/span><\/p>\n<p><span style=\"color: #000000;\">\u672c\u7814\u7a76\u6210\u679c\u306f\uff0c<a href=\"https:\/\/www.hokudai.ac.jp\/news\/2021\/08\/post-892.html\">\u5317\u5927\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9\uff08https:\/\/www.hokudai.ac.jp\/news\/2021\/08\/post-892.html\uff09<\/a>\u306b\u3082\u63b2\u8f09\u3055\u308c\u3066\u3044\u307e\u3059\u306e\u3067\uff0c\u3088\u308a\u8a73\u3057\u3044\u5185\u5bb9\u306f\u305d\u3061\u3089\u306e\u8a18\u4e8b\u3082\u3054\u89a7\u4e0b\u3055\u3044\u3002<\/span><\/p>\n<p><a href=\"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-content\/uploads\/2021\/08\/1-TOC.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-5142\" src=\"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-content\/uploads\/2021\/08\/1-TOC-300x104.png\" alt=\"\" width=\"549\" height=\"190\" srcset=\"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-content\/uploads\/2021\/08\/1-TOC-300x104.png 300w, https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-content\/uploads\/2021\/08\/1-TOC-768x266.png 768w, https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-content\/uploads\/2021\/08\/1-TOC-1024x354.png 1024w\" sizes=\"auto, (max-width: 549px) 100vw, 549px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u3092\u72d9\u3044\u6483\u3061\u3059\u308b\u764c\u5149\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u306b\u6210\u529f \uff5e\u526f\u4f5c\u7528\u306e\u5c11\u306a\u3044\u764c\u6cbb\u7642\u3092\uff0c\u30df\u30c8\u30b3\u30f3\u30c9\u30ea\u30a2\u306b\u85ac\u3092\u904b\u3076\u6280\u8853\u958b\u767a\u3067\uff01\uff5e \u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u85ac\u5b66\u7814\u7a76\u9662\u306e\u5c71\u7530\u52c7\u78e8\u51c6\u6559\u6388\uff0c\u539f\u5cf6\u79c0\u5409\u6559\u6388\u3068\u96fb\u5b50\u79d1\u5b66\u7814\u7a76\u6240\u306e\u9ad8\u91ce\u52c7\u592a\u51c6\u6559\u6388\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"class_list":["post-5138","post","type-post","status-publish","format-standard","hentry","category-sci"],"_links":{"self":[{"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/posts\/5138","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/comments?post=5138"}],"version-history":[{"count":8,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/posts\/5138\/revisions"}],"predecessor-version":[{"id":5147,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/posts\/5138\/revisions\/5147"}],"wp:attachment":[{"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/media?parent=5138"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/categories?post=5138"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/tags?post=5138"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}