{"id":5747,"date":"2022-04-12T19:37:29","date_gmt":"2022-04-12T10:37:29","guid":{"rendered":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/?p=5747"},"modified":"2022-04-12T19:37:29","modified_gmt":"2022-04-12T10:37:29","slug":"%e6%a4%8d%e7%89%a9%e3%81%ae%e3%83%90%e3%82%a4%e3%82%aa%e3%83%9e%e3%82%b9%e5%a2%97%e5%8a%a0%e3%82%92%e6%94%af%e3%81%88%e3%82%8b%e8%84%b1%e3%83%a6%e3%83%93%e3%82%ad%e3%83%81%e3%83%b3%e5%8c%96%e9%85%b5","status":"publish","type":"post","link":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/5747.html","title":{"rendered":"\u690d\u7269\u306e\u30d0\u30a4\u30aa\u30de\u30b9\u5897\u52a0\u3092\u652f\u3048\u308b\u8131\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u9175\u7d20\u3092\u767a\u898b\uff5e\u690d\u7269\u30db\u30eb\u30e2\u30f3\u306e\u4f5c\u7528\u52b9\u679c\u3092\u9ad8\u3081\u308b\u65b0\u305f\u306a\u624b\u6cd5\u306e\u958b\u767a\u306b\u671f\u5f85\uff5e"},"content":{"rendered":"

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\n<\/strong>\uff5e\u690d\u7269\u30db\u30eb\u30e2\u30f3\u306e\u4f5c\u7528\u52b9\u679c\u3092\u9ad8\u3081\u308b\u65b0\u305f\u306a\u624b\u6cd5\u306e\u958b\u767a\u306b\u671f\u5f85\uff5e<\/strong><\/h2>\n

\u3010\u30dd\u30a4\u30f3\u30c8\u3011<\/strong><\/h3>\n

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\n\u30fb\u690d\u7269\u30db\u30eb\u30e2\u30f3\u300c\u30d6\u30e9\u30b7\u30ce\u30b9\u30c6\u30ed\u30a4\u30c9\u300d\u306e\u53d7\u5bb9\u4f53\u30bf\u30f3\u30d1\u30af\u8cea\u91cf\u3092\u7dad\u6301\u3059\u308b\u305f\u3081\u306bUBP12\/13\u304c\u91cd\u8981\u3002
\n\u30fb\u30d6\u30e9\u30b7\u30ce\u30b9\u30c6\u30ed\u30a4\u30c9\u306b\u3088\u308b\u690d\u7269\u6210\u9577\u4fc3\u9032\u52b9\u679c\u3092\u5f37\u5316\u3059\u308b\u305f\u3081\u306e\u65b0\u305f\u306a\u624b\u6cd5\u306e\u958b\u767a\u306b\u671f\u5f85\u3002<\/p>\n

\u3010\u6982\u8981\u3011<\/h3>\n

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\n\u690d\u7269\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308b\u30d6\u30e9\u30b7\u30ce\u30b9\u30c6\u30ed\u30a4\u30c9\u306f\uff0c\u830e\u306e\u4f38\u9577\u3084\u8449\u9762\u7a4d\u306e\u62e1\u5927\u3092\u306f\u3058\u3081\u3068\u3057\u3066\uff0c\u690d\u7269\u306e\u6210\u9577\u4fc3\u9032\u306b\u6975\u3081\u3066\u91cd\u8981\u306a\u5f79\u5272\u3092\u62c5\u3044\u307e\u3059\u3002\u30d6\u30e9\u30b7\u30ce\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u958b\u59cb\u3059\u308b\u306e\u304c\uff0c\u7d30\u80de\u819c\u306b\u5c40\u5728\u3059\u308b\u53d7\u5bb9\u4f53BRI1\u3067\u3042\u308a\uff0c\u7d30\u80de\u4e2d\u306eBRI1\u306e\u5b58\u5728\u91cf\u306f\uff0c\u30d6\u30e9\u30b7\u30ce\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u5f37\u5ea6\u3092\u9069\u5207\u306b\u5236\u5fa1\u3059\u308b\u4e0a\u3067\u91cd\u8981\u3067\u3059\u3002BRI1\u306e\u5b58\u5728\u91cf\u306f\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u4fee\u98fe*2<\/sup>\u306b\u3088\u308a\u8a98\u5c0e\u3055\u308c\u308b\u6db2\u80de\u5206\u89e3\u306b\u3088\u3063\u3066\u8abf\u7bc0\u3055\u308c\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u306a\u304c\u3089\uff0cBRI1\u306e\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u30ec\u30d9\u30eb\u304c\u3069\u306e\u3088\u3046\u306a\u4ed5\u7d44\u307f\u3067\u9069\u5207\u306b\u4fdd\u305f\u308c\u3066\u3044\u308b\u304b\u306f\u672a\u89e3\u660e\u306e\u307e\u307e\u3067\u3057\u305f\u3002
\n\u4eca\u56de\uff0c\u5171\u540c\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\uff0c\u8131\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u9175\u7d20UBP12\/13\u304cBRI1\u3068\u76f8\u4e92\u4f5c\u7528\u3057\uff0c\u76f4\u63a5\u7684\u306bBRI1\u306e\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u4fee\u98fe\u3092\u53d6\u308a\u5916\u3059\u3053\u3068\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002UBP12\/13\u3092\u6b20\u640d\u3059\u308b\u5909\u7570\u682a\u3067\u306f\uff0c\u904e\u5270\u306a\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u4fee\u98fe\u3068\u6db2\u80de\u5206\u89e3*3<\/sup>\u306b\u3088\u3063\u3066BRI1\u91cf\u304c\u6e1b\u5c11\u3057\uff0c\u305d\u306e\u7d50\u679c\uff0c\u690d\u7269\u500b\u4f53\u30b5\u30a4\u30ba\u304c\u8457\u3057\u304f\u4f4e\u4e0b\u3059\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002\u690d\u7269\u306b\u304a\u3044\u3066\uff0c\u819c\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6db2\u80de\u5206\u89e3\u3092\u6291\u5236\u3059\u308b\u8131\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u9175\u7d20\u306e\u767a\u898b\u306f\u4e16\u754c\u521d\u306e\u6210\u679c\u3067\u3059\u3002
\n\u672c\u7814\u7a76\u6210\u679c\u306f\uff0c\u690d\u7269\u7d30\u80de\u306e\u819c\u5c40\u5728\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5b58\u5728\u91cf\u3092\u9069\u5207\u306b\u4fdd\u3064\u305f\u3081\u306e\u5206\u5b50\u6a5f\u69cb\u89e3\u660e\u306b\u5411\u3051\u305f\u91cd\u8981\u306a\u77e5\u898b\u3092\u63d0\u4f9b\u3059\u308b\u3068\u540c\u6642\u306b\uff0c\u30d6\u30e9\u30b7\u30ce\u30b9\u30c6\u30ed\u30a4\u30c9\u306b\u3088\u308b\u690d\u7269\u6210\u9577\u4fc3\u9032\u52b9\u679c\u3092\u5f37\u5316\u3059\u308b\u305f\u3081\u306e\u65b0\u305f\u306a\u624b\u6cd5\u306e\u958b\u767a\u306b\u3064\u306a\u304c\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002
\n\u672c\u7814\u7a76\u6210\u679c\u306f\uff0c2022\u5e742\u670815\u65e5\uff08\u706b\uff09\u306bEMBO reports<\/em>\u8a8c\u306b\u30aa\u30f3\u30e9\u30a4\u30f3\u63b2\u8f09\u3055\u308c\u308b\u3068\u3068\u3082\u306b\uff0c4\u6708\u53f7\u306e\u8868\u7d19\u3092\u98fe\u308a\u307e\u3057\u305f\u3002<\/p>\n

\u3010\u80cc\u666f\u3011<\/strong><\/h3>\n

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\n\u3053\u308c\u307e\u3067\u306b\uff0c \u7d30\u80de\u819c\u4e0a\u306eBRI1\u306f\uff0c\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u4fee\u98fe\u3092\u53d7\u3051\u308b\u3053\u3068\u3067\u7d30\u80de\u5185\u3078\u79fb\u884c\u3057\uff0c\u6700\u7d42\u7684\u306b\u306f\u6db2\u80de\u3078\u904b\u3070\u308c\u5206\u89e3\u3055\u308c\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u3057\u304b\u3057\uff0cBRI1\u306e\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u30ec\u30d9\u30eb\u304c\u3069\u306e\u3088\u3046\u306a\u4ed5\u7d44\u307f\u3067\u9069\u5207\u306b\u4fdd\u305f\u308c\uff0cBRI1\u5b58\u5728\u91cf\u3092\u898f\u5b9a\u3057\u3066\u3044\u308b\u304b\u306f\u672a\u89e3\u660e\u306e\u307e\u307e\u3067\u3059\u3002<\/p>\n

\u3010\u7814\u7a76\u624b\u6cd5\u3068\u6210\u679c\u3011<\/strong><\/h3>\n

\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\uff0c\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u4fee\u98fe\u306b\u95a2\u308f\u308b\u56e0\u5b50\u306e\u4e2d\u3067\u3082\uff0c\u6a19\u7684\u304b\u3089\u30e6\u30d3\u30ad\u30c1\u30f3\u3092\u53d6\u5916\u3059\u201c\u8131\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u9175\u7d20\u201d\u306e\u6a5f\u80fd\u306b\u7740\u76ee\u3057\u305f\u7814\u7a76\u306b\u53d6\u7d44\u307f\u307e\u3057\u305f\u3002\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u4fee\u98fe\u306f\u53ef\u9006\u7684\u306a\u30bf\u30f3\u30d1\u30af\u8cea\u7ffb\u8a33\u5f8c\u4fee\u98fe\u3067\u3042\u308a\uff0c\u30e6\u30d3\u30ad\u30c1\u30f3\u30ea\u30ac\u30fc\u30bc\uff08\u3048\u3093\u3074\u3064\uff09\u304c\u6a19\u7684\u306b\u30e6\u30d3\u30ad\u30c1\u30f3\u3092\u4ed8\u52a0\u3059\u308b\u4e00\u65b9\u3067\uff0c\u8131\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u9175\u7d20\uff08\u6d88\u3057\u30b4\u30e0\uff09\u304c\u30e6\u30d3\u30ad\u30c1\u30f3\u3092\u9664\u53bb\u3059\u308b\u6d3b\u6027\u3092\u6709\u3057\u307e\u3059\u3002\u8fd1\u5e74\u306e\u7814\u7a76\u304b\u3089\uff0c\u3053\u306e\u300c\u6d88\u3057\u30b4\u30e0\u300d\u306e\u5f79\u5272\u304c\u7d30\u80de\u5185\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u91cf\u3092\u9069\u5207\u306b\u7dad\u6301\u3059\u308b\u306e\u306b\u91cd\u8981\u306a\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u304d\u307e\u3057\u305f\u3002
\n\u305d\u3053\u3067\uff0c\u30e2\u30c7\u30eb\u690d\u7269\u30b7\u30ed\u30a4\u30cc\u30ca\u30ba\u30ca\u3092\u7528\u3044\u305f\u5206\u5b50\u907a\u4f1d\u5b66\u7684\u306a\u89e3\u6790\u3092\u884c\u3063\u305f\u7d50\u679c\uff0c\u8131\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u9175\u7d20UBP13\u3068\u305d\u306e\u30db\u30e2\u30ed\u30b0\u3067\u3042\u308bUBP12\u306e\u4e8c\u91cd\u5909\u7570\u682a\uff08ubp12\/13<\/em>\uff09\u3067\u306f\uff0c\u690d\u7269\u306e\u6210\u9577\u304c\u8457\u3057\u304f\u963b\u5bb3\u3055\u308c\uff0c\u77ee\u5c0f\u5316\u3059\u308b\u3053\u3068\u3092\u898b\u51fa\u3057\u307e\u3057\u305f\uff08\u56f31\uff09\u3002\u3053\u306e\u8868\u73fe\u578b\u306f\uff0c\u3053\u308c\u307e\u3067\u306b\u5831\u544a\u3055\u308c\u3066\u3044\u305fBRI1\u5909\u7570\u682a\u306e\u8868\u73fe\u578b\u3068\u975e\u5e38\u306b\u985e\u4f3c\u3059\u308b\u5f62\u8cea\u3067\u3057\u305f\u3002\u305d\u3053\u3067\uff0cubp12\/13<\/em>\u682a\u5185\u306eBRI1\u30bf\u30f3\u30d1\u30af\u8cea\u91cf\u3092\u8abf\u3079\u305f\u7d50\u679c\uff0c\u91ce\u751f\u578b\u682a\u306b\u6bd4\u3079\u3066BRI1\u30bf\u30f3\u30d1\u30af\u8cea\u91cf\u304c\u6e1b\u5c11\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5206\u304b\u308a\u307e\u3057\u305f\u3002\u3055\u3089\u306b\uff0cUBP13\u3068BRI1\u304c\u690d\u7269\u7d30\u80de\u5185\u3067\u76f8\u4e92\u4f5c\u7528\u3057\u3066\u304a\u308a\uff0cUBP13\u306fBRI1\u306b\u4ed8\u52a0\u3055\u308c\u305f\u30e6\u30d3\u30ad\u30c1\u30f3\u4fee\u98fe\u3092\u76f4\u63a5\u7684\u306b\u9664\u53bb\u3059\u308b\u6d3b\u6027\u304c\u3042\u308b\u3053\u3068\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002
\n\u3053\u308c\u306b\u52a0\u3048\u3066\uff0c\u5171\u7126\u70b9\u30ec\u30fc\u30b6\u30fc\u9855\u5fae\u93e1*4<\/sup>\u3092\u7528\u3044\u305f\u8a73\u7d30\u306a\u30e9\u30a4\u30d6\u30bb\u30eb\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u89e3\u6790\u3092\u884c\u3063\u305f\u7d50\u679c\uff0cubp12\/13<\/em>\u682a\u5185\u3067\u306f\uff0c\u6db2\u80de\u306b\u904b\u3070\u308c\u5206\u89e3\u3092\u53d7\u3051\u308bBRI1\u91cf\u304c\u904e\u5270\u306b\u306a\u3063\u3066\u304a\u308a\uff0c\u7d30\u80de\u819c\u4e0a\u306eBRI1\u91cf\u304c\u6e1b\u3063\u3066\u3044\u308b\u3053\u3068\u3082\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\uff08\u56f32\uff09\u3002\u307e\u305f\uff0c\u9762\u767d\u3044\u7d50\u679c\u3068\u3057\u3066\uff0cBRI1\u306e\u7279\u5b9a\u306e\u30ea\u30b8\u30f3\u6b8b\u57fa\u306b\u5909\u7570\u3092\u5c0e\u5165\u3057\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u3092\u53d7\u3051\u306a\u3044\u72b6\u614b\u306b\u3057\u305fBRI1\uff08BRI1KR\uff09\u3092ubp12\/13<\/em>\u682a\u5185\u306b\u767a\u73fe\u3055\u305b\u305f\u7d50\u679c\uff0c\u7d30\u80de\u819c\u4e0a\u306eBRI1\u91cf\u304c\u5897\u52a0\u3057\uff0c\u690d\u7269\u306e\u500b\u4f53\u30b5\u30a4\u30ba\u3082\u5927\u5e45\u306b\u56de\u5fa9\u3057\u307e\u3057\u305f\uff08\u56f31\uff09\u3002
\n\u672c\u7814\u7a76\u7d50\u679c\u304b\u3089\uff0c\u7d30\u80de\u306b\u304a\u3051\u308b\u9069\u5207\u306aBRI1\u91cf\u306e\u7dad\u6301\u306b\u306f\u8131\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u9175\u7d20UBP12\/13\u306e\u6d3b\u6027\u304c\u91cd\u8981\u3067\u3042\u308a\uff0c\u30d6\u30e9\u30b7\u30ce\u30b9\u30c6\u30ed\u30a4\u30c9\u306b\u3088\u308b\u690d\u7269\u306e\u6210\u9577\u4fc3\u9032\u306b\u6b20\u304b\u305b\u306a\u3044\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\uff08\u56f33\uff09\u3002\u690d\u7269\u3067\u306f\uff0cBRI1\u4ee5\u5916\u306b\u3082\uff0c\u7d30\u80de\u819c\u4e0a\u306e\u53d7\u5bb9\u4f53\u3084\u6804\u990a\u7d20\u306e\u8f38\u9001\u4f53\u3082\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u4fee\u98fe\u4f9d\u5b58\u7684\u306b\u6db2\u80de\u306b\u304a\u3044\u3066\u5206\u89e3\u3055\u308c\u308b\u3053\u3068\u304c\u5206\u304b\u3063\u3066\u304d\u3066\u3044\u307e\u3059\u304c\uff0c\u3053\u306e\u30d7\u30ed\u30bb\u30b9\u3092\u6291\u5236\u3059\u308b\u8131\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u9175\u7d20\u306f\u3053\u308c\u307e\u3067\u77e5\u3089\u308c\u3066\u304a\u3089\u305a\uff0c\u4eca\u56de\u304c\u521d\u3081\u3066\u306e\u767a\u898b\u3067\u3059\u3002<\/p>\n

\u3010\u4eca\u5f8c\u3078\u306e\u671f\u5f85\u3011<\/strong><\/h3>\n

\u672c\u7814\u7a76\u6210\u679c\u306f\uff0c\u690d\u7269\u7d30\u80de\u306e\u819c\u5c40\u5728\u30bf\u30f3\u30d1\u30af\u8cea\u91cf\u3092\u9069\u5207\u306b\u4fdd\u3064\u305f\u3081\u306e\u5206\u5b50\u6a5f\u69cb\u89e3\u660e\u306b\u5411\u3051\u305f\u91cd\u8981\u306a\u77e5\u898b\u3092\u63d0\u4f9b\u3059\u308b\u3082\u306e\u3067\u3059\u3002\u307e\u305f\uff0cUBP12\/13\u3068BRI1\u306e\u76f8\u4e92\u4f5c\u7528\u3084\u8131\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u6d3b\u6027\u5236\u5fa1\u6a5f\u69cb\u306e\u8a73\u7d30\u304c\u89e3\u660e\u3055\u308c\u308b\u3053\u3068\u3067\uff0c\u30d6\u30e9\u30b7\u30ce\u30b9\u30c6\u30ed\u30a4\u30c9\u306b\u3088\u308b\u690d\u7269\u6210\u9577\u4fc3\u9032\u52b9\u679c\u3092\u5f37\u5316\u3059\u308b\u305f\u3081\u306e\u65b0\u305f\u306a\u624b\u6cd5\u306e\u958b\u767a\u306b\u7e4b\u304c\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n

\u672c\u7814\u7a76\u6210\u679c\u306b\u3064\u3044\u3066\u306f\u3001\u5317\u5927\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9(https:\/\/www.hokudai.ac.jp\/news\/2022\/02\/post-990.html<\/a>)\u306b\u3082\u63b2\u8f09\u3055\u308c\u3066\u304a\u308a\u307e\u3059\u3002\u4f75\u305b\u3066\u3054\u89a7\u4e0b\u3055\u3044\u3002<\/p>\n

\u3010\u8ad6\u6587\u60c5\u5831\u3011<\/strong><\/h3>\n

\u8ad6\u6587\u540d\u3000Deubiquitinating enzymes UBP12 and UBP13 stabilize the brassinosteroid receptor BRI1\uff08\u8131\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u9175\u7d20UBP12\u3068UBP13\u306f\u30d6\u30e9\u30b7\u30ce\u30b9\u30c6\u30ed\u30a4\u30c9\u53d7\u5bb9\u4f53BRI1\u3092\u5b89\u5b9a\u5316\u3055\u305b\u308b\uff09
\n\u8457\u8005\u540d\u3000Yongming Luo 1<\/sup>\uff0c\u9ad8\u6728\u7d14\u5e732<\/sup>, Lucas Alves Neubus Claus 3,4<\/sup>, Chao Zhang5<\/sup>, \u5b89\u7530\u76db\u8cb42<\/sup>, \u9577\u8c37\u5ddd\u967d\u5b501<\/sup>, \u5c71\u53e3\u6df3\u4e8c2<\/sup>, Libo Shan 6<\/sup>, Eugenia Russinova 3,4<\/sup>, \u4f50\u85e4\u9577\u7dd22<\/sup>\uff081<\/sup>\u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u751f\u547d\u79d1\u5b66\u9662\uff0c2<\/sup>\u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u7406\u5b66\u7814\u7a76\u9662\uff0c3<\/sup> \u30b2\u30f3\u30c8\u5927\u690d\u7269\u30d0\u30a4\u30aa\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u30fb\u30d0\u30a4\u30aa\u30a4\u30f3\u30d5\u30a9\u30de\u30c6\u30a3\u30af\u30b9\u5b66\u79d1\uff0c4<\/sup> \u690d\u7269\u30b7\u30b9\u30c6\u30e0\u30d0\u30a4\u30aa\u30ed\u30b8\u30fc\u7814\u7a76\u30bb\u30f3\u30bf\u30fc\uff08VIB\uff09\uff0c5<\/sup> \u30c6\u30ad\u30b5\u30b9A&M\u5927\u5b66\u690d\u7269\u75c5\u7406\u30fb\u5fae\u751f\u7269\u5b66\u79d1\uff0c6<\/sup> \u30c6\u30ad\u30b5\u30b9A&M\u5927\u5b66\u751f\u5316\u5b66\u30fb\u751f\u7269\u7269\u7406\u5b66\u79d1\uff09
\n\u96d1\u8a8c\u540d\u3000EMBO reports<\/em>\uff08\u6b27\u5dde\u5206\u5b50\u751f\u7269\u5b66\u6a5f\u69cb\u8a8c\uff09
\n\uff24\uff2f\uff29\u300010.15252\/embr.202153354<\/a>
\n\u516c\u8868\u65e5\u30002022\u5e742\u670815\u65e5\uff08\u706b\uff09\uff08\u30aa\u30f3\u30e9\u30a4\u30f3\u516c\u958b\uff09<\/p>\n

\"\"<\/a><\/p>\n

\u56f31<\/strong>. \u91ce\u751f\u578b\u682a\u53ca\u3073ubp12\/13<\/em>\u682a\uff0cBRI1KR\u5c0e\u5165ubp12\/13<\/em>\u682a\u306e\u751f\u80b2<\/p>\n

\"\"<\/a><\/p>\n

\u56f32<\/strong>. \u91ce\u751f\u578b\u682a\u53ca\u3073ubp12\/13<\/em>\u682a\u306e\u7d30\u80de\u5185\u306b\u304a\u3051\u308b\u86cd\u5149\u30e9\u30d9\u30eb\u5316\u30d6\u30e9\u30b7\u30ce\u30b9\u30c6\u30ed\u30a4\u30c9\u306e\u53d6\u8fbc\u307f\u5b9f\u9a13\uff08\u86cd\u5149\u5f37\u5ea6\u304c\u6db2\u80de\u5206\u89e3\u3092\u53d7\u3051\u305fBRI1\u91cf\u3092\u8868\u3059\uff09<\/p>\n

\"\"<\/a><\/p>\n

\u56f33<\/strong>. \u8131\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u9175\u7d20UBP12\/13\u306b\u3088\u308bBRI1\u306e\u5b58\u5728\u91cf\u5236\u5fa1\u30e2\u30c7\u30eb
\n\u7d30\u80de\u819c\u4e0a\u306eBRI1\u306f\uff0c\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u4fee\u98fe\u3092\u53d7\u3051\u3066\u7d30\u80de\u5185\u306e\u5185\u819c\u7cfb\u30aa\u30eb\u30ac\u30cd\u30e9\uff08TGN\/EE\uff0cMVB\uff09\u306b\u79fb\u884c\u3057\uff0c\u6700\u7d42\u7684\u306b\u6db2\u80de\u306b\u304a\u3044\u3066\u5206\u89e3\u3055\u308c\u308b\u3002UBP12\/13\u306f\uff0cBRI1\u306e\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u3092\u9664\u53bb\u3059\u308b\u3053\u3068\u3067\uff0c\u6db2\u80de\u5206\u89e3\u3092\u6291\u5236\u3057\uff0c\u7d30\u80de\u819c\u4e0a\u306eBRI1\u91cf\u3092\u9069\u5207\u306b\u4fdd\u3064\u3002<\/p>\n

\u3010\u7528\u8a9e\u89e3\u8aac\u3011<\/strong><\/h3>\n

\uff0a1 \u00a0\u30d6\u30e9\u30b7\u30ce\u30b9\u30c6\u30ed\u30a4\u30c9 \u2026 \u690d\u7269\u306e\u5408\u6210\u3059\u308b\u30b9\u30c6\u30ed\u30a4\u30c9\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308a\uff0c\u830e\u306e\u4f38\u9577\u3084\u8449\u9762\u7a4d\u306e\u62e1\u5927\u3092\u306f\u3058\u3081\uff0c\u690d\u7269\u306e\u6210\u9577\u4fc3\u9032\u306b\u95a2\u4e0e\u3059\u308b\u3002\u6697\u6240\u3067\u306e\u80da\u8ef8\u4f38\u9577\u3082\u5236\u5fa1\u3059\u308b\u3002
\n\uff0a2 \u00a0\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u4fee\u98fe\uff0c\u8131\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u9175\u7d20 \u2026 \u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u4fee\u98fe\u306f\uff0c76\u30a2\u30df\u30ce\u9178\u6b8b\u57fa\u304b\u3089\u306a\u308b\u30e6\u30d3\u30ad\u30c1\u30f3\u5206\u5b50\u3092\u4ed8\u52a0\u3059\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u7ffb\u8a33\u5f8c\u4fee\u98fe\u306e\u4e00\u7a2e\u3002\u30e6\u30d3\u30ad\u30c1\u30f3\u304c\u8907\u6570\u500b\u3064\u306a\u304c\u3063\u305f\u30dd\u30ea\u30e6\u30d3\u30ad\u30c1\u30f3\u9396\u3092\u5f62\u6210\u3057\uff0c\u6a19\u7684\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u5206\u89e3\u3084\u7d30\u80de\u5185\u5c40\u5728\u6027\u7b49\u3092\u5236\u5fa1\u3059\u308b\u30b7\u30b0\u30ca\u30eb\u3068\u306a\u308b\u3002\u8131\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u9175\u7d20\u306f\uff0c\u6a19\u7684\u304b\u3089\u30e6\u30d3\u30ad\u30c1\u30f3\u9396\u3092\u53d6\u308a\u9664\u304f\u6d3b\u6027\u3092\u6709\u3059\u308b\u3002
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