{"id":6608,"date":"2023-06-05T16:02:58","date_gmt":"2023-06-05T07:02:58","guid":{"rendered":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/?p=6608"},"modified":"2023-06-05T16:02:58","modified_gmt":"2023-06-05T07:02:58","slug":"%e5%be%ae%e7%94%9f%e7%89%a9%e3%81%ae%e3%82%82%e3%81%a4%e7%b7%bb%e5%af%86%e3%81%aa%e5%90%ab%e7%aa%92%e7%b4%a0%e8%a4%87%e7%b4%a0%e7%92%b0%e5%90%88%e6%88%90%e7%b5%8c%e8%b7%af%e3%82%92%e8%a7%a3%e6%98%8e","status":"publish","type":"post","link":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/6608.html","title":{"rendered":"\u5fae\u751f\u7269\u306e\u3082\u3064\u7dfb\u5bc6\u306a\u542b\u7a92\u7d20\u8907\u7d20\u74b0\u5408\u6210\u7d4c\u8def\u3092\u89e3\u660e\uff5e\u6709\u7528\u306a\u8907\u7d20\u74b0\u306e\u52b9\u7387\u7684\u306a\u5408\u6210\u6cd5\u306e\u78ba\u7acb\u306b\u671f\u5f85\uff5e\uff08\u85ac\u5b66\u7814\u7a76\u9662\u3000\u6559\u6388\u3000\u8107\u672c\u654f\u5e78\u3001\u8b1b\u5e2b\u3000\u677e\u7530\u7814\u4e00\uff09"},"content":{"rendered":"

\u30dd\u30a4\u30f3\u30c8<\/h3>\n

\u25cfActinopyridazinone\u306e\u751f\u5408\u6210\u7d4c\u8def\u306e\u5168\u5bb9\u3092\u89e3\u660e\u3002
\n\u25cfDihydropyridazinone\u74b0\u304c\u3001\u4fdd\u8b77\u57fa\u306e\u7740\u8131\u3092\u9375\u3068\u3059\u308b\u7dfb\u5bc6\u306a\u7d4c\u8def\u306b\u3088\u3063\u3066\u751f\u5408\u6210\u3055\u308c\u308b\u3053\u3068\u3092\u89e3\u660e\u3002
\n\u25cf\u5fae\u751f\u7269\u306e\u3082\u3064\u542b\u7a92\u7d20\u8907\u7d20\u74b0\u5408\u6210\u7d4c\u8def\u306e\u591a\u69d8\u6027\u3092\u89e3\u660e\u3002<\/p>\n

\u6982\u8981<\/h3>\n

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\u542b\u7a92\u7d20\u8907\u7d20\u74b0\u306f\u3001\u533b\u85ac\u54c1\u306e\u958b\u767a\u73fe\u5834\u3067\u76db\u3093\u306b\u5229\u7528\u3055\u308c\u308b\u6709\u7528\u306a\u9aa8\u683c\u3067\u3042\u308a\u3001\u672c\u7814\u7a76\u3067\u751f\u5408\u6210\u6a5f\u69cb\u304c\u660e\u3089\u304b\u306b\u306a\u3063\u305fdihydropyridazinone\u74b0\u3082\u3044\u304f\u3064\u304b\u306e\u533b\u85ac\u54c1\u306b\u542b\u307e\u308c\u308b\u6709\u7528\u306a\u9aa8\u683c\u3067\u3059\u3002\u4eca\u56de\u660e\u3089\u304b\u306b\u306a\u3063\u305f\u751f\u5408\u6210\u306e\u4ed5\u7d44\u307f\u3092\u6d3b\u7528\u3059\u308b\u3053\u3068\u3067\u3001\u4eca\u5f8c\u3001\u533b\u85ac\u54c1\u539f\u6599\u3068\u306a\u308b\u6709\u7528\u306a\u5206\u5b50\u3092\u52b9\u7387\u3088\u304f\u5408\u6210\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n

\u306a\u304a\u3001\u672c\u7814\u7a76\u306e\u6210\u679c\u306f\u30012023\u5e745\u670817\u65e5\u516c\u958b\u306eAngewandte Chemie International Edition\u8a8c\u306b\u30aa\u30f3\u30e9\u30a4\u30f3\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u8ad6\u6587\u540d\uff1aCarrier Protein Mediated Formation of the Dihydropyridazinone ring in Actinopyridazinone Biosynthesis\uff08\u7279\u7570\u306a\u524d\u99c6\u4f53\u304b\u3089\u30d2\u30c9\u30e9\u30b8\u30f3\u5408\u6210\u9175\u7d20\u306b\u3088\u3063\u3066\u751f\u5408\u6210\u3055\u308c\u308b\u30b8\u30d2\u30c9\u30ed\u30d4\u30ea\u30c0\u30b8\u30ce\u30f3\u9aa8\u683c\u542b\u6709\u5929\u7136\u7269\uff09
\nURL\uff1ahttps:\/\/doi.org\/10.1002\/anie.202305155<\/a><\/p>\n

\u8a73\u7d30\u306f\u3053\u3061\u3089<\/a><\/p>\n

<\/a>
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