{"id":6740,"date":"2023-09-15T19:01:18","date_gmt":"2023-09-15T10:01:18","guid":{"rendered":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/?p=6740"},"modified":"2023-09-15T19:01:18","modified_gmt":"2023-09-15T10:01:18","slug":"b%e7%b4%b0%e8%83%9e%e6%8a%97%e4%bd%93%e7%94%a3%e7%94%9f%e3%82%92%e5%88%b6%e5%be%a1%e3%81%99%e3%82%8b%e3%82%a2%e3%83%80%e3%83%97%e3%82%bf%e3%83%bc%e5%88%86%e5%ad%90%e3%82%92%e7%99%ba%e8%a6%8b%ef%bd%9e","status":"publish","type":"post","link":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/6740.html","title":{"rendered":"B\u7d30\u80de\u6297\u4f53\u7523\u751f\u3092\u5236\u5fa1\u3059\u308b\u30a2\u30c0\u30d7\u30bf\u30fc\u5206\u5b50\u3092\u767a\u898b\uff5e\u30a2\u30ec\u30eb\u30ae\u30fc\u6cbb\u7642\u85ac\u958b\u767a\u3078\u306e\u8ca2\u732e\u306b\u671f\u5f85\uff5e\uff08\u85ac\u5b66\u7814\u7a76\u9662\u3000\u6559\u6388\u3000\u677e\u7530\u3000\u6b63\uff09"},"content":{"rendered":"<h3>\u30dd\u30a4\u30f3\u30c8<\/h3>\n<p>\u25cf\u6297\u4f53\u7523\u751f\u3092\u62c5\u3046B\u7d30\u80de\u5185\u306e\u3001STAP-2\u3068\u547c\u3070\u308c\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6a5f\u80fd\u3092\u89e3\u6790\u3002<br 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Letters\u8a8c\u30672023\u5e749\u67085\u65e5\u306b\u30aa\u30f3\u30e9\u30a4\u30f3\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<p>\u8ad6\u6587\u540d\uff1aSTAP-2 negatively regulates BCR-mediated B cell activation by recruiting Csk to Lyn\uff08STAP-2\u306fLyn\u3078Csk\u3092\u52d5\u54e1\u3059\u308b\u3053\u3068\u3067BCR\u4ecb\u5728B\u7d30\u80de\u6d3b\u6027\u5316\u53cd\u5fdc\u3092\u8ca0\u306b\u5236\u5fa1\u3059\u308b\uff09<br \/>\nURL\uff1a<a href=\"https:\/\/doi.org\/10.1002\/1873-3468.14730\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1002\/1873-3468.14730<\/a><\/p>\n<p>\u8a73\u7d30\u306f<a href=\"https:\/\/www.hokudai.ac.jp\/news\/pdf\/230908_pr.pdf\" target=\"_blank\" rel=\"noopener\">\u3053\u3061\u3089<\/a><\/p>\n<p><a href=\"https:\/\/www.hokudai.ac.jp\/news\/img\/230908_pr_pic.jpg\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.hokudai.ac.jp\/news\/img\/230908_pr_pic.jpg\" width=\"400\" \/><\/a><br \/>\n\u672c\u7814\u7a76\u306b\u3088\u308b\u65b0\u305f\u306aB\u7d30\u80de\u6297\u4f53\u7523\u751f\u5236\u5fa1\u30e1\u30ab\u30cb\u30ba\u30e0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30dd\u30a4\u30f3\u30c8 \u25cf\u6297\u4f53\u7523\u751f\u3092\u62c5\u3046B\u7d30\u80de\u5185\u306e\u3001STAP-2\u3068\u547c\u3070\u308c\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6a5f\u80fd\u3092\u89e3\u6790\u3002 \u25cfSTAP-2\u3092\u6b20\u640d\u3057\u305f\u30de\u30a6\u30b9\u3067\u306fB\u7d30\u80de\u5185Lyn\u6d3b\u6027\u5316\u304c\u4ea2\u9032\u3057\u3001\u6297\u4f53\u7523\u751f\u304c\u5897\u5f37\u3002 \u25cfSTAP-2\u306fCsk\u3068\u76f8\u4e92\u4f5c\u7528\u3059\u308b\u3053\u3068\u3067\u3001Lyn\u306e [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"class_list":["post-6740","post","type-post","status-publish","format-standard","hentry","category-sci"],"_links":{"self":[{"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/posts\/6740","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/comments?post=6740"}],"version-history":[{"count":1,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/posts\/6740\/revisions"}],"predecessor-version":[{"id":6742,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/posts\/6740\/revisions\/6742"}],"wp:attachment":[{"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/media?parent=6740"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/categories?post=6740"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/tags?post=6740"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}