{"id":7150,"date":"2024-05-09T20:48:56","date_gmt":"2024-05-09T11:48:56","guid":{"rendered":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/?p=7150"},"modified":"2024-05-09T20:48:57","modified_gmt":"2024-05-09T11:48:57","slug":"%e5%85%89%e3%82%92%e4%bd%bf%e3%81%a3%e3%81%9f%e5%87%9d%e9%9b%86%e4%bd%93%e6%a9%9f%e8%83%bd%e9%9a%9c%e5%ae%b3%e3%81%a8%e3%81%9d%e3%81%ae%e5%be%8c%e3%81%ae%e7%b4%b0%e8%83%9e%e9%81%8b%e5%91%bd%e8%a7%a3","status":"publish","type":"post","link":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/7150.html","title":{"rendered":"\u5149\u3092\u4f7f\u3063\u305f\u51dd\u96c6\u4f53\u6a5f\u80fd\u969c\u5bb3\u3068\u305d\u306e\u5f8c\u306e\u7d30\u80de\u904b\u547d\u89e3\u6790\u306b\u6210\u529f\uff08\u5148\u7aef\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662\u30fb\u5317\u6751 \u6717 \u8b1b\u5e2b\uff09"},"content":{"rendered":"\n

\uff5e\u907a\u4f1d\u5b50\u7834\u58ca\u6280\u8853\u3067\u306f\u9054\u6210\u3067\u304d\u306a\u3044\u7d30\u80de\u5185\u975e\u819c\u30aa\u30eb\u30ac\u30cd\u30e9\u306e\u6a5f\u80fd\u89e3\u660e\u306b\u671f\u5f85\uff5e<\/strong><\/p>\n\n\n\n

\u30dd\u30a4\u30f3\u30c8
\u30fb\u5149\u3092\u7528\u3044\u3066\u7d30\u80de\u5185\u51dd\u96c6\u4f53\u3067\u3042\u308b\u30b9\u30c8\u30ec\u30b9\u9846\u7c92\u306b\u6a5f\u80fd\u969c\u5bb3\u3092\u5f15\u304d\u8d77\u3053\u3055\u305b\u308b\u3053\u3068\u306b\u6210\u529f\u3002
\u30fb\u30b9\u30c8\u30ec\u30b9\u9846\u7c92\u306e\u6a5f\u80fd\u969c\u5bb3\u306b\u3088\u308a\u7d30\u80de\u6b7b\u304c\u8d77\u3053\u308b\u3053\u3068\u3092\u5b9f\u8a3c\u3002
\u30fb\u69d8\u3005\u306a\u7d30\u80de\u5185\u975e\u819c\u30aa\u30eb\u30ac\u30cd\u30e9\u306e\u751f\u7406\u7684\u5f79\u5272\u89e3\u660e\u3068\u75be\u60a3\u539f\u56e0\u51dd\u96c6\u4f53\u306e\u7834\u58ca\u7642\u6cd5\u306b\u671f\u5f85\u3002<\/p>\n\n\n\n

\u3000\u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u5148\u7aef\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662\u306e\u5317\u6751 \u6717\u8b1b\u5e2b\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u5358\u91cf\u4f53\u8d64\u8272\u86cd\u5149\u30bf\u30f3\u30d1\u30af\u8cea\uff08\u4ee5\u4e0b SuperNova-Red\uff0a1 <\/sup>\uff09\u3092\u7d30\u80de\u5185\u306e\u30b9\u30c8\u30ec\u30b9\u9846\u7c92\uff0a2<\/sup>\u3078\u5c40\u5728\u5316\u3055\u305b\u305f\u5f8c\u3001\u5149\u3092\u7167\u5c04\u3059\u308b\u3053\u3068\u3067\u3001\u6642\u7a7a\u9593\u3092\u5236\u5fa1\u3057\u3064\u3064\u3001\u30b9\u30c8\u30ec\u30b9\u9846\u7c92\u306e\u6a5f\u80fd\u969c\u5bb3\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u53ef\u80fd\u306a\u5149\u907a\u4f1d\u5b66\u6cd5\uff0a3<\/sup> \u306e\u958b\u767a\u306b\u6210\u529f\u3057\u307e\u3057\u305f\u3002\u5149\u907a\u4f1d\u5b66\u3068\u306f\u3001\u5149\u3067\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6a5f\u80fd\u3084\u6d3b\u6027\u3092\u5236\u5fa1\u3059\u308b\u6280\u8853\u306e\u7dcf\u79f0\u3067\u3059\u3002\u4ee3\u8868\u7684\u306a\u5149\u907a\u4f1d\u5b66\u306e\u65b9\u6cd5\u3067\u306f\u5149\u3067\u5236\u5fa1\u3055\u308c\u308b\u30a4\u30aa\u30f3\u30c1\u30e3\u30cd\u30eb\u3084\u30a4\u30aa\u30f3\u30dd\u30f3\u30d7\u306a\u3069\u306e\u6d3b\u6027\u3092\u5236\u5fa1\u3059\u308b\u65b9\u6cd5\u304c\u77e5\u3089\u308c\u3066 \u3044\u307e\u3059\u304c\u3001\u672c\u6210\u679c\u3067\u306f\u86cd\u5149\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u5149\u3092\u7167\u5c04\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u30bf\u30b0\u4ed8\u3051\u3057\u305f\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6a5f\u80fd\u3092\u4e0d\u6d3b\u6027\u5316\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u767a\u8272\u56e3\u88dc\u52a9\u5149\u4e0d\u6d3b\u5316\u6cd5\uff08CALI \u6cd5\uff09\uff0a4<\/sup>\u3092\u30b9\u30c8\u30ec\u30b9\u9846\u7c92\u306b\u9069\u7528\u3057\u3001\u305d\u306e\u5f8c\u7d30\u80de\u306b\u8d77\u3053\u308b\u904b\u547d\u3092\u89e3\u660e\u3057\u305f\u3082\u306e\u3067\u3059\u3002
\u3000\u7d30\u80de\u5185\u306b\u306f\u69d8\u3005\u306a\u51dd\u96c6\u4f53\u306e\u5b58\u5728\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u3053\u308c\u3089\u533a\u753b\u306e\u7279\u5fb4\u7684\u306a\u6a5f\u80fd\u3092\u8abf\u3079\u308b\u65b9\u6cd5\u306f\u3053\u308c\u307e\u3067\u78ba\u7acb\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u7279\u306b\u3001\u907a\u4f1d\u5b50\u5de5\u5b66\u306e\u624b\u6cd5\u3067\u3042\u308b\u907a\u4f1d\u5b50\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u3084\u30ce\u30c3\u30af\u30c0\u30a6\u30f3\u3068\u3044\u3063\u305f\u65b9\u6cd5\u3092\u7528\u3044\u308b\u3068\u3001\u7d30\u80de\u5185\u306e\u5bfe\u8c61\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3059\u3079\u3066\u5408\u6210\u3055\u308c\u306a\u304f\u306a\u308b\u3053\u3068\u304b\u3089\u3001\u51dd\u96c6\u4f53\u305d\u306e\u3082\u306e\u3082\u5f62\u6210\u3055\u308c\u306a\u304f\u306a\u308a\u3001\u305d\u306e\u6a5f\u80fd\u3092\u8abf\u3079\u308b\u3053\u3068\u304c\u539f\u7406\u4e0a\u4e0d\u53ef\u80fd\u3067\u3057\u305f\u3002
\u3000\u305d\u306e\u305f\u3081\u3001\u6642\u7a7a\u9593\u3092\u5236\u5fa1\u3057\u3064\u3064\u51dd\u96c6\u4f53\u306e\u6a5f\u80fd\u969c\u5bb3\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u3067\u304d\u308b\u65b0\u3057\u3044\u624b\u6cd5\u304c\u5fc5\u8981\u3067\u3042\u308a\u3001\u672c\u7814\u7a76\u306f\u305d\u306e\u5b9f\u8a3c\u3092\u884c\u3063\u305f\u3082\u306e\u3067\u3059\u3002\u672c\u7814\u7a76\u306b\u3088\u308a\u958b\u767a\u3057\u305f\u5149\u907a\u4f1d\u5b66\u5b9f\u9a13\u6cd5\u306f\u3001\u7d30\u80de\u5185\u306e\u69d8\u3005\u306a\u6a5f\u80fd\u6027\u69cb\u9020\u306e\u89e3\u6790\u306b\u5fdc\u7528\u3055\u305b\u308b\u3053\u3068\u306b\u3088\u308a\u3001\u975e\u819c\u30aa\u30eb\u30ac\u30cd\u30e9\u6a5f\u80fd\u306e\u5168\u8c8c\u89e3\u660e\u3084\u75be\u60a3\u306e\u539f\u56e0\u3068\u306a\u308b\u51dd\u96c6\u4f53\u7834\u58ca\u7642\u6cd5\u306e\u305f\u3081\u306e\u30c4\u30fc\u30eb\u3068\u306a\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002
\u3000\u306a\u304a\u3001\u672c\u7814\u7a76\u6210\u679c\u306f\u30012024 \u5e74 5 \u6708 3 \u65e5\uff08\u91d1\uff09\u516c\u958b\u306e ACS Omega \u8a8c\u306b\u30aa\u30f3\u30e9\u30a4\u30f3\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

<\/p>\n\n\n

\n
\"\"<\/a><\/figure>\n<\/div>\n\n\n

\u7d30\u80de\u5185\u306b\u5f62\u6210\u3055\u308c\u305f\u30b9\u30c8\u30ec\u30b9\u9846\u7c92\u3068\u3001\u305d\u308c\u306b\u5bfe\u3059\u308b\u5149\u907a\u4f1d\u5b66\u7684\u7834\u58ca\u6cd5\uff08CALI \u6cd5\uff09\u306e\u9069\u5fdc\u3002<\/p>\n\n\n\n

\u8a73\u7d30\u306f\u4ee5\u4e0b\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n

\u5317\u5927\u30d7\u30ec\u30b9\u30ea\u30ea\u30fc\u30b9\uff1a\u5149\u3092\u4f7f\u3063\u305f\u51dd\u96c6\u4f53\u6a5f\u80fd\u969c\u5bb3\u3068\u305d\u306e\u5f8c\u306e\u7d30\u80de\u904b\u547d\u89e3\u6790\u306b\u6210\u529f\uff5e\u907a\u4f1d\u5b50\u7834\u58ca\u6280\u8853\u3067\u306f\u9054\u6210\u3067\u304d\u306a\u3044\u7d30\u80de\u5185\u975e\u819c\u30aa\u30eb\u30ac\u30cd\u30e9\u306e\u6a5f\u80fd\u89e3\u660e\u306b\u671f\u5f85\uff5e<\/a><\/p>\n\n\n\n

\u8ad6\u6587\u60c5\u5831\uff1a
\u8ad6\u6587\u540d\uff1a Stress granule dysfunction via chromophore-associated light inactivation\uff08\u767a\u8272\u56e3\u88dc\u52a9\u5149
\u4e0d\u6d3b\u5316\u6cd5\u306b\u3088\u308b\u30b9\u30c8\u30ec\u30b9\u9846\u7c92\u306e\u6a5f\u80fd\u969c\u5bb3\uff09
\u8457\u8005\u540d\uff1a \u9bc9\u4f4f\u62d3\u672a 1<\/sup>\u3001\u85e4\u672c \u611b 1<\/sup>\u3001\u5ddd\u53e3\u9065\u9999 1<\/sup>\u3001\u9ed2\u5d0e \u7d2c 1<\/sup>\u3001\u5317\u6751 \u6717 2<\/sup>\uff081<\/sup>\u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u751f\u547d\u79d1\u5b66\u9662\u30012<\/sup>\u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u5148\u7aef\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662\uff09
\u96d1\u8a8c\u540d\uff1a ACS Omega\uff08\u7c73\u56fd\u5316\u5b66\u4f1a\u767a\u884c\u306e\u5b66\u8853\u8a8c\uff09
\uff24\uff2f\uff29\uff1a 10.1021\/<\/a>acsomega<\/a>.<\/a>4c01469<\/a>
\u516c\u8868\u65e5 \uff1a2024 \u5e74 5 \u6708 3 \u65e5\uff08\u91d1\uff09\uff08\u30aa\u30f3\u30e9\u30a4\u30f3\u516c\u958b\uff09<\/p>\n\n\n\n

<\/p>\n\n\n\n

\u3010\u7528\u8a9e\u89e3\u8aac\u3011
\uff0a1 <\/sup>SuperNova-Red<\/strong> \u2026 \u5358\u91cf\u4f53\u578b\u8d64\u8272\u86cd\u5149\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u4e00\u3064\u3002\u4e16\u754c\u3067\u521d\u3081\u3066\u958b\u767a\u3055\u308c\u305f\u907a\u4f1d\u5b50\u30b3\u30fc\u30c9\u578b\u306e\u5149\u5897\u611f\u5264\u3092\u5358\u91cf\u4f53\u578b\u306b\u6539\u5909\u3057\u3001\u6a19\u7684\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u5bfe\u3057\u30bf\u30b0\u4ed8\u3051\u3092\u884c\u3044\u3084\u3059\u304f\u3057\u305f\u3082\u306e\u3002\u5b87\u5b99\u306b\u304a\u3051\u308b\u8d85\u65b0\u661f\u7206\u767a\u304b\u3089\u540d\u4ed8\u3051\u3089\u308c\u305f\u3002
\uff0a2<\/sup> \u30b9\u30c8\u30ec\u30b9\u9846\u7c92<\/strong> \u2026 \u9ad8\u5869\u6fc3\u5ea6\u3001\u9ad8\u9178\u5316\u3001\u9ad8\u6d78\u900f\u5727\u306a\u3069\u306e\u30b9\u30c8\u30ec\u30b9\u74b0\u5883\u4e0b\u306b\u7f6e\u304b\u308c\u305f\u7d30\u80de\u5185\u3067\u3001\u7d30\u80de\u8cea\u306b\u5f62\u6210\u3055\u308c\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u6838\u9178\uff08RNA\uff09\u304b\u3089\u69cb\u6210\u3055\u308c\u308b\u51dd\u96c6\u4f53\u306e\u4e00\u3064\u3002\u30b9\u30c8\u30ec\u30b9\u304b\u3089\u89e3\u653e\u3055\u308c\u308b\u3068\u6d88\u5931\u3059\u308b\u3002
\uff0a3 <\/sup>\u5149\u907a\u4f1d\u5b66\u6cd5<\/strong> \u2026 \u5149\u3092\u4f7f\u3063\u3066\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u6a5f\u80fd\u3084\u6d3b\u6027\u3092\u5236\u5fa1\u3059\u308b\u6280\u8853\u306e\u7dcf\u79f0\u3002\u7d30\u80de\u306e\u307f\u306a\u3089\u305a\u500b\u4f53\u306b\u304a\u3051\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u767a\u73fe\u91cf\u3084\u884c\u52d5\u306a\u3069\u69d8\u3005\u306a\u751f\u7269\u30d7\u30ed\u30bb\u30b9\u3092\u5236\u5fa1\u3067\u304d\u308b\u3053\u3068\u304b\u3089\u300c\u907a\u4f1d\u5b66\u300d\u3068\u3044\u3046\u540d\u79f0\u304c\u3064\u3051\u3089\u308c\u3066\u3044\u308b\u3002\u5143\u6765\u3001\u5149\u3092\u5229\u7528\u3057\u3066\u3044\u306a\u3044\u751f\u7269\u306b\u5bfe\u3057\u3066\u3082\u9069\u5fdc\u53ef\u80fd\u3067\u3042\u308b\u3002
\uff0a4<\/sup> \u767a\u8272\u56e3\u88dc\u52a9\u5149\u4e0d\u6d3b\u5316\u6cd5\uff08CALI \u6cd5\uff09<\/strong>\u2026 Chromophore-assisted light inactivation \u306e\u7565\u79f0\u3067\u3001\u53cd\u5fdc\u6027\u306e\u9ad8\u3044\u6d3b\u6027\u9178\u7d20\u7a2e\u3092\u7523\u751f\u3057\u3084\u3059\u3044\u86cd\u5149\u5206\u5b50\u3084\u86cd\u5149\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u6a19\u7684\u30bf\u30f3\u30d1\u30af\u8cea\u3068\u878d\u5408\u3057\u3066\u7d30\u80de\u5185\u3078\u5c0e\u5165\u307e\u305f\u306f\u767a\u73fe\u3055\u305b\u3001\u5149\u7167\u5c04\u306b\u3088\u308a\u6a19\u7684\u30bf\u30f3\u30d1\u30af\u8cea\u53ca\u3073\u305d\u308c\u306b\u8fd1\u63a5\u3059\u308b\u751f\u4f53\u5206\u5b50\u3092\u4e0d\u6d3b\u5316\u3059\u308b\u624b\u6cd5\u306e\u3053\u3068\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

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