{"id":8626,"date":"2026-10-28T12:16:55","date_gmt":"2026-10-28T03:16:55","guid":{"rendered":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/?p=8626"},"modified":"2026-11-04T12:23:44","modified_gmt":"2026-11-04T03:23:44","slug":"%e7%b4%b0%e8%8f%8c%e3%81%ae%e7%b4%b0%e8%83%9e%e5%88%86%e8%a3%82%e3%82%92%e5%8f%b8%e3%82%8b%e3%80%8c%e5%88%86%e8%a3%82%e9%85%b5%e7%b4%a0%e8%a4%87%e5%90%88%e4%bd%93%e3%80%8d%e3%81%ae%e5%8b%95%e4%bd%9c","status":"publish","type":"post","link":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/8626.html","title":{"rendered":"\u7d30\u83cc\u306e\u7d30\u80de\u5206\u88c2\u3092\u53f8\u308b\u300c\u5206\u88c2\u9175\u7d20\u8907\u5408\u4f53\u300d\u306e\u52d5\u4f5c\u539f\u7406\u3092\u89e3\u660e\uff5e\u6297\u83cc\u85ac\u958b\u767a\u306b\u65b0\u305f\u306a\u6a19\u7684\u3001FtsW-FtsI\u306e\u5354\u8abf\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u4e16\u754c\u3067\u521d\u3081\u3066\u63d0\u793a\uff5e\uff08\u85ac\u5b66\u7814\u7a76\u9662\u3000\u6559\u6388\u3000\u5e02\u5ddd\u3000\u8061\uff09"},"content":{"rendered":"<p>2026\u5e7410\u670828\u65e5<\/p>\n<p>\u30dd\u30a4\u30f3\u30c8<br \/>\n\u25cf\u7d30\u83cc\u304c\u7d30\u80de\u5206\u88c2\u6642\u306b\u65b0\u3057\u3044\u7d30\u80de\u58c1\u3092\u4f5c\u308b\u4ed5\u7d44\u307f\u3092\u4e16\u754c\u3067\u521d\u3081\u3066\u89e3\u660e\u3002<br \/>\n\u25cf\u4e8c\u3064\u306e\u9175\u7d20FtsW\u3068FtsI\u304c\u3001\u300c\u4e8c\u3064\u306e\u69cb\u9020\u72b6\u614b\u300d\u3092\u5207\u308a\u66ff\u3048\u3066\u5354\u8abf\u3057\u3066\u50cd\u304f\u3053\u3068\u3092\u767a\u898b\u3002<br \/>\n\u25cf\u77ed\u9396\u578blipid II\u8a98\u5c0e\u4f53\u304c\u9175\u7d20\u6d3b\u6027\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u3092\u793a\u3057\u3001\u65b0\u898f\u6297\u83cc\u85ac\u306e\u5275\u85ac\u6a19\u7684\u3068\u3057\u3066\u6709\u671b\u3002<\/p>\n<p>\u6982\u8981<br \/>\n\u5317\u6d77\u9053\u5927\u5b66\u5927\u5b66\u9662\u85ac\u5b66\u7814\u7a76\u9662\u306e\u5e02\u5ddd\u3000\u8061\u6559\u6388\u3089\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u30c7\u30e5\u30fc\u30af\u5927\u5b66\u306e\u30bd\u30af\u30e8\u30f3\u30ea\u30fc\u6c0f\u3068\u306e\u56fd\u969b\u5171\u540c\u7814\u7a76\u306b\u3088\u308a\u3001\u7d30\u83cc\u306e\u7d30\u80de\u5206\u88c2\u306b\u5fc5\u9808\u306a\u300cFtsWIQLB\u8907\u5408\u4f53\u300d\u304c\u3069\u306e\u3088\u3046\u306b\u7d30\u80de\u58c1\u3092\u4f5c\u308a\u4e0a\u3052\u308b\u306e\u304b\u3001\u305d\u306e\u5206\u5b50\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u7d30\u83cc\u306f\u7d30\u80de\u5206\u88c2\u306e\u969b\u3001\u30da\u30d7\u30c1\u30c9\u30b0\u30ea\u30ab\u30f3\u3092\u65b0\u3057\u304f\u5408\u6210\u3057\u3001\u3053\u308c\u304c\u7d30\u83cc\u306e\u7d30\u80de\u58c1\u3068\u306a\u308a\u307e\u3059\u3002\u3053\u306e\u5408\u6210\u306fFtsW\u3068FtsI\u3068\u3044\u3046\u4e8c\u3064\u306e\u9175\u7d20\u304c\u5354\u529b\u3057\u3066\u9032\u3081\u307e\u3059\u304c\u3001\u4e21\u8005\u304c\u3069\u306e\u3088\u3046\u306b\u9023\u643a\u3057\u3066\u300c\u7cd6\u9396\u306e\u4f38\u9577\u300d\u3068\u300c\u30da\u30d7\u30c1\u30c9\u67b6\u6a4b\u300d\u3092\u540c\u671f\u3055\u305b\u3066\u3044\u308b\u306e\u304b\u306f\u9577\u5e74\u306e\u8b0e\u3067\u3057\u305f\u3002\u672c\u7814\u7a76\u3067\u306f\u3001\u30af\u30e9\u30a4\u30aa\u96fb\u5b50\u9855\u5fae\u93e1\uff08Cryo-EM\uff09\u3001AlphaFold\u306b\u3088\u308b\u69cb\u9020\u4e88\u6e2c\u3001\u751f\u5316\u5b66\u7684\u89e3\u6790\u3001\u5316\u5b66\u5408\u6210\u3057\u305flipid II\u8a98\u5c0e\u4f53\u306a\u3069\u3092\u7d44\u307f\u5408\u308f\u305b\u3001FtsW\u3068FtsI\u304c\u300cdown\u69cb\u9020\uff08\u4e0d\u6d3b\u6027\u578b\uff09\u300d\u3068\u300cup\u69cb\u9020\uff08\u6d3b\u6027\u578b\uff09\u300d\u306e\u4e8c\u3064\u306e\u72b6\u614b\u3092\u5207\u308a\u66ff\u3048\u306a\u304c\u3089\u30da\u30d7\u30c1\u30c9\u30b0\u30ea\u30ab\u30f3\u3092\u5408\u6210\u3059\u308b\u3053\u3068\u3092\u767a\u898b\u3057\u307e\u3057\u305f\u3002\u7279\u306b\u3001FtsI\u306b\u5b58\u5728\u3059\u308b\u300ccoupling helix\u300d\u304cFtsW\u306e\u50cd\u304d\u3092\u76f4\u63a5\u5236\u5fa1\u3059\u308b\u3053\u3068\u3092\u793a\u3057\u3001\u4e21\u9175\u7d20\u304c\u7269\u7406\u7684\u306b\u9023\u52d5\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u7cd6\u9396\u304c11\u30e6\u30cb\u30c3\u30c8\u4ee5\u4e0a\u306e\u9577\u3055\u306b\u306a\u3089\u306a\u3044\u3068\u67b6\u6a4b\u53cd\u5fdc\u304c\u59cb\u307e\u3089\u306a\u3044\u3053\u3068\u3092\u767a\u898b\u3057\u3001\u7d30\u80de\u58c1\u5408\u6210\u306e\u300c\u9577\u3055\u306e\u6761\u4ef6\u300d\u3092\u521d\u3081\u3066\u63d0\u793a\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306e\u6210\u679c\u306f\u3001\u6297\u83cc\u85ac\u8010\u6027\u304c\u4e16\u754c\u7684\u306b\u6df1\u523b\u5316\u3059\u308b\u4e2d\u3001FtsWIQLB\u8907\u5408\u4f53\u304c\u65b0\u305f\u306a\u6297\u83cc\u85ac\u6a19\u7684\u3068\u306a\u308a\u5f97\u308b\u3053\u3068\u3092\u793a\u3059\u3082\u306e\u3067\u3059\u3002<\/p>\n<p>\u306a\u304a\u3001\u672c\u7814\u7a76\u6210\u679c\u306f\u30012026\u5e7410\u670822\u65e5\uff08\u6728\uff09\u516c\u958b\u306eNature Communications\u8a8c\u306b\u30aa\u30f3\u30e9\u30a4\u30f3\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<p>\u8ad6\u6587\u540d\uff1aMolecular basis of coupled peptidoglycan synthesis by the FtsWIQLB divisome complex from Vibrio cholerae\uff08\u30b3\u30ec\u30e9\u83cc FtsWIQLB \u30c7\u30a3\u30d3\u30bd\u30fc\u30e0\u8907\u5408\u4f53\u306b\u3088\u308b\u30da\u30d7\u30c1\u30c9\u30b0\u30ea\u30ab\u30f3\u5408\u6210\u5354\u8abf\u6a5f\u69cb\u306e\u5206\u5b50\u57fa\u76e4\uff09<br \/>\nURL\uff1a<a href=\"https:\/\/doi.org\/10.1038\/s41467-026-78795-0\">https:\/\/doi.org\/10.1038\/s41467-026-78795-0<\/p>\n<p><\/a>\u8a73\u7d30\u306f<a href=\"https:\/\/www.hokudai.ac.jp\/news\/pdf\/261028_pr.pdf\">\u3053\u3061\u3089<\/a><\/p>\n<div id=\"attachment_8627\" style=\"width: 510px\" class=\"wp-caption aligncenter\"><a href=\"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-content\/uploads\/2026\/11\/\u5e02\u5ddd\u5148\u751f\uff08261028\uff09-e1793762138616.png\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-8627\" class=\"size-full wp-image-8627\" src=\"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-content\/uploads\/2026\/11\/\u5e02\u5ddd\u5148\u751f\uff08261028\uff09-e1793762138616.png\" alt=\"\" width=\"500\" height=\"207\" \/><\/a><p id=\"caption-attachment-8627\" class=\"wp-caption-text\">FtsWIQLB\u6d3b\u6027\u5316\u306e\u4f5c\u696d\u30e2\u30c7\u30eb\u3002\u5de6\uff1a\u4e0d\u6d3b\u6027\u306a\u300cdown\u300d\u69cb\u9020\u3067\u306f\u3001FtsI\u6d3b\u6027\u90e8\u4f4d\u306f\u96a0\u3055\u308c\u3001\u30da\u30d7\u30c1\u30c9\u30b0\u30ea\u30ab\u30f3\u5408\u6210\u53cd\u5fdc\u306f\u8d77\u3053\u3089\u306a\u3044\u3002\u4e2d\u592e\uff1alipid II\u7d50\u5408\u306b\u3088\u308aFtsW\u304c\u91cd\u5408\u3092\u958b\u59cb\u3057\u3001FtsI\u30da\u30ea\u30d7\u30e9\u30ba\u30e0\u30c9\u30e1\u30a4\u30f3\u304c\u7d0490\u00b0\u56de\u8ee2\u3057\u3066\u6d3b\u6027\u90e8\u4f4d\u304c\u9732\u51fa\u3059\u308b\u3002\u53f3\uff1a\u6d3b\u6027\u578b\u300cup\u300d\u69cb\u9020\u3067\u306f\u3001\u7cd6\u9396\u306e\u7e70\u308a\u8fd4\u3057\u6570\u304c\u95be\u5024\uff08n &gt; 11\uff09\u3092\u8d85\u3048\u308b\u3068FtsI\u6d3b\u6027\u90e8\u4f4d\u306b\u5230\u9054\u3057\u3001\u91cd\u5408\u3068\u67b6\u6a4b\u53cd\u5fdc\u304c\u9032\u884c\u3059\u308b\u3002<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"<p>2026\u5e7410\u670828\u65e5 \u30dd\u30a4\u30f3\u30c8 \u25cf\u7d30\u83cc\u304c\u7d30\u80de\u5206\u88c2\u6642\u306b\u65b0\u3057\u3044\u7d30\u80de\u58c1\u3092\u4f5c\u308b\u4ed5\u7d44\u307f\u3092\u4e16\u754c\u3067\u521d\u3081\u3066\u89e3\u660e\u3002 \u25cf\u4e8c\u3064\u306e\u9175\u7d20FtsW\u3068FtsI\u304c\u3001\u300c\u4e8c\u3064\u306e\u69cb\u9020\u72b6\u614b\u300d\u3092\u5207\u308a\u66ff\u3048\u3066\u5354\u8abf\u3057\u3066\u50cd\u304f\u3053\u3068\u3092\u767a\u898b\u3002 \u25cf\u77ed\u9396\u578blipid II\u8a98\u5c0e\u4f53 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[],"class_list":["post-8626","post","type-post","status-publish","format-standard","hentry","category-sci"],"_links":{"self":[{"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/posts\/8626","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/comments?post=8626"}],"version-history":[{"count":5,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/posts\/8626\/revisions"}],"predecessor-version":[{"id":8632,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/posts\/8626\/revisions\/8632"}],"wp:attachment":[{"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/media?parent=8626"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/categories?post=8626"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lfsci.hokudai.ac.jp\/info\/wp-json\/wp\/v2\/tags?post=8626"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}